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Michael Zhang


Dr. Zhang's backgrounds include medicine with an MD and Master of clinical oncology from Peking University Health Science Center and environmental toxicology with a PhD from University of California, Riverside. Work experience ranges from practicing general surgery, new drug development and submission in phases from pre-clinical development to clinical trials, construction of physiologically based pharmacokinetic and pharmacodynamic (PBPK/PD) models, and human exposure/risk assessment for environmental toxicants. Currently working as a research scientist, Dr. Zhang's research interests include clinical outcome studies using large databases to improve clinical practice and healthcare use, and surgical procedures and devices to improve treatment.


Selected Publications      

Zhang X, He L, Lu Y, Liu M, Huang X. Androgen receptor in primary hepatocellular carcinoma and its clinical significance. Chin Med J (Engl) 1998;111(12):1083-6.

Zhang X, Tsang AM, Okino MS, Power FW, Knaak JB, Harrison LS, and Dary CC. A Physiologically Based Pharmacokinetic/Pharmacodynamic Model for Carbofuran in Sprague-Dawley Rats Using the Exposure Related Dose Estimating Model. Toxicol Sci 2007;100(2),345-59.

Zhang X, Driver JH, Li YH, Ross JH, Krieger RI. Dialkylphosphates (DAPs) in fruits and vegetables may confound biomonitoring in organophosphorus insecticide exposure and risk assessment. J Agric Food Chem 2008;56 (22):10638-645.


Zhang X, Acevedo S, Chao Y, Chen Z, Dinoff T, Driver J, Ross J, Williams R, Krieger R. Concurrent 2,4-D and triclopyr biomonitoring of backpack applicators, mixer/loader and field supervisor in forestry. Journal of Environmental Science and Health Part B Pesticides Food Contaminants and Agricultural Wastes 2011; 46(4):281-93.


Book Chapter

Zhang X, Knaak JB, Tornero-Velez R,Blancato JN, Dary CC. Application of physiologically based pharmacokinetic/pharmacodynamic modeling in cumulative risk assessment for N-methyl carbamate insecticides. In Handbook of Pesticide Toxicology 3rd edition, Robert Krieger. Elsevier, 2010; Chapter 73:1591-605.